Guidelines for submission of abstracts
Authors are suggested to follow the guidelines carefully while preparing the abstracts. Full length article will be published in the forthcoming issue of Journal of Laboratory Animal Science. Hence, authors should submit the full length article upon acceptance of the abstract. Abstract should be concise and should be no more than 250 words. Plan the abstract as a single paragraph that is unified (i.e., one topic) and coherent (i.e., ideas flow continuously). Two (maybe even three) paragraphs are also acceptable so long as the abstract as a whole is unified/coherent. Edit it carefully for grammar, punctuation, typos, etc. Please submit your abstract electronically to firstname.lastname@example.org no later than October 31, 2018. Abstract will be considered for publication only if registration fee is paid.
In order to assist with the review/editing of abstracts, please carefully observe the following formatting and style conventions:
- Titles should be Arial Bold 14 point single spaced.
- Author information should be set two lines below the title and in Arial 11 point. It should consist of three lines single spaced: your name, your department/school, your institution.
- The body of the abstract should be set two lines below your author information.
- Font should be Arial 11 point.
- Line spacing should be 1.5 with double spacing between paragraphs.
- Text should be set left, non-justified, block paragraph/s (no indent).
- Margins should be set at 2.54cm on top, bottom and right, with a 3.5cm margin on the left.
- There should be two spaces after the end punctuation of each sentence in the text.
- Avoid abbreviations such as “e.g.,” “i.e.,” “etc.”—that is, spell out the words.
Total Leucocytes and Lymphocytes correlates with T cell deficiency and not on B or NK cell deficiency in mice
Shailendra Arindkar, Srikanth Iyer, Jerald Mahesh Kumar and Nagarajan Perumal
Experimental Animal Facility, National Institute of Immunology, New Delhi - 100 067, India
The objective of this study was to compare changes in leucocyte and lymphocyte analytes in various models of immunodeficient mice lacking T or B or NK cells or both T and B cells. In this study, we used the following immunodeficient mice (nu; T inactive B+ NK+), (IgH-6-/-; T+B inactive NK+) (beige; T+B+NK inactive) and SCID and RAG-1-/- (T inactive B inactive NK+). Among the T cell deficient (Ii-/-, CD8+, CD4 Inactive) and (TAP-1-/-; CD 4 inactive and CD8+) were used. FACS analyses of peripheral-blood mononuclear cells were performed to determine the percentage of CD3+ T cell, B220 + B cell and NK cell along with analysis of hematological parameters. There were marked differences in the relative proportions of leucocytes and lymphocytes blood cell population among the immunodeficient strains. These results indicate that WBC and lymphocytes population in whole blood depends on T cells percentage. B cells and NK cells deficiency has minor role in the leucocytes and lymphocytes population in immunodeficient status in mouse models. The hematological differences described here are based on the level of CD3, B220 and NK1.1 cells. This study will provide baseline information for researchers who use various immunodeficient mice for immunological, genetic and cancer studies.